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Car slams into crowd in LA injuring at least 30 (VIDEO)
Car slams into crowd in LA injuring at least 30 (VIDEO)

Russia Today

time3 days ago

  • Russia Today

Car slams into crowd in LA injuring at least 30 (VIDEO)

At least 30 people were injured, seven of them critically, when an 'unknown vehicle' slammed into a crowd in East Hollywood after midnight on Saturday, according to the Los Angeles Fire Department (LAFD). A preliminary investigation has suggested the driver may have lost consciousness before colliding, Captain Adam Van Gerpen, the public information officer for the LAFD, has said, as quoted by Newsweek. The crash occurred at around 2am near a music venue. Van Gerpen reported that a line of people had been waiting to enter a nightclub when a Nissan Versa struck them, also hitting a taco truck and a valet stand. Car plows into crowd in Los Angeles, injuring at least 20Emergency services descended on Santa Monica Boulevard in East Hollywood after a vehicle smashed into pedestrians at around 2am local time.#LosAngeles#Emergency#SantaMonica#EastHollywood#CarCrash# Paramedics found that one of the patients had a gunshot wound, according to Van Gerpen. He added that the identity of this individual was not yet known. 'This is under police investigation. This will be a large investigation with the LAPD,' Van Gerpen said. Videos circulating online show the aftermath of the crash, with emergency vehicles at the scene. Earlier, on Friday, an explosion rocked the Los Angeles County Sheriff's Department training facility, killing at least three veteran deputies. The department has not said what they were doing at the time or what caused the explosion, the Associated Press has said.

Kayne Anderson BDC, Inc. Announces Investment in SG Credit Partners, Inc., a Leading Lower Middle Market Credit Platform
Kayne Anderson BDC, Inc. Announces Investment in SG Credit Partners, Inc., a Leading Lower Middle Market Credit Platform

Globe and Mail

time7 days ago

  • Business
  • Globe and Mail

Kayne Anderson BDC, Inc. Announces Investment in SG Credit Partners, Inc., a Leading Lower Middle Market Credit Platform

Kayne Anderson BDC, Inc. (NYSE: KBDC) ('KBDC' or the 'Company'), a business development company externally managed by its investment adviser, KA Credit Advisors, LLC, an affiliate of Kayne Anderson Capital Advisors, LP ('Kayne Anderson'), today announced an investment in SG Credit Partners, Inc. (along with affiliates and subsidiaries; 'SG Credit'), a national credit platform focused on the lower middle market to complement KBDC's middle market investing strategy. SG Credit was formed in 2013 and has invested in more than 200 companies, originating over $1.0 billion in commitments across its three lending verticals (Commercial Finance, Consumer Products, and Software & Technology). With offices in Newport Beach, Santa Monica, Atlanta, Boston, and Chicago, SG Credit plans to use its expanded capital base to grow existing verticals and develop adjacent businesses. The investment complements KBDC's private credit investment capabilities by further diversifying proprietary investment channels and will be structured as an $80.0 million term loan facility, $34.0 million delayed draw term loan facility and $12.0 million common equity investment. KBDC anticipates that its debt investment in SG Credit will be immediately accretive to earnings in 2025. KBDC will also be a significant minority shareholder in SG Credit following the closing of the transaction. 'This is a key strategic opportunity for KBDC and highlights our commitment to growing our portfolio with value-enhancing investments,' said Doug Goodwillie, Co-Chief Executive Officer of KBDC. 'SG Credit's unique lower middle market lending platform is highly complementary to our business and will further enhance the returns of KBDC's diversified portfolio.' 'There have been a number of highly successful investments by BDCs and credit managers into asset-based platforms and finance companies in the past few years,' said Frank Karl, Senior Vice President of KBDC. 'We have known the team at SG Credit for many years and they have delivered a strong track record of returns for their investors. We think that their investment culture is well-aligned with KBDC's and are excited to partner with the team to provide a greater breadth of financing solutions to our clients.' SG Credit Chairman Mack McNair commented, 'We appreciate Kayne Anderson's confidence in SG Credit. Their investment, combined with continued support and incremental investment from 4612 Group and The Cynosure Group, is a validation of the business we are building with Marc Cole, Charlie Perer, Andrew Hettinger, and the entire SG Credit team. With this investment, SG Credit is well-positioned in its pursuit of sound, profitable, growth as a leading multi-product credit platform serving the lower middle market.' 'We are proud and excited to partner with a firm of the caliber and history of Kayne Anderson. This collaboration will not only support our growth with additional capital but also enable us to offer innovative, value-added financing solutions to a wider range of companies,' said Marc Cole, Co-Founder and Chief Executive Officer of SG Credit. Fenchurch Advisory Partners US LP is serving as financial advisor and Mayer Brown LLP is acting as legal advisor to KBDC. Solomon Partners is serving as financial advisor and Greenberg Traurig LLP and Brenner, Saltzman & Wallman LLP are acting as legal advisors to SG Credit. About Kayne Anderson BDC, Inc. Kayne Anderson BDC, Inc. is a business development company ('BDC') that invests primarily in first lien senior secured loans, with a secondary focus on unitranche and split-lien loans to middle market companies. KBDC is externally managed by its investment adviser, KA Credit Advisors, LLC, an indirect controlled subsidiary of Kayne Anderson Capital Advisors, L.P., a prominent alternative investment management firm. KBDC has elected to be regulated as a BDC under the Investment Company Act of 1940, as amended ('1940 Act'). KBDC's investment objective is to generate current income and, to a lesser extent, capital appreciation. For more information, please visit About SG Credit Partners, Inc. SG Credit Partners ('SGCP'), is a national private credit manager providing capital to lower middle market businesses and entrepreneurs requiring tailored credit solutions. SGCP has established a broad credit platform consisting of three verticals: Software + Technology, Consumer Products, and Commercial Finance. Headquartered in Southern California with offices throughout the country, the firm has provided in excess of $1 billion to lower middle market entrepreneurs across a variety of industries. About 4612 Group 4612 Group is an Atlanta-based investment firm and Registered Investment Advisor. 4612's team has more than 20 years of experience investing alongside one another and focuses primarily on direct investments where it partners with founders and management owners of mid-sized businesses throughout the US. About The Cynosure Group The Cynosure Group is a Salt Lake City based diversified investment firm that supports family offices, foundations, endowments, and like-minded investors who are seeking to build their wealth and maximize their impact in the world. Cynosure's direct growth equity investments target partnerships with founders and management-owners of profitable small to mid-sized North American-based companies who will remain meaningful owners of their business. Forward-looking Statements This press release may contain 'forward-looking statements' that involve substantial risks and uncertainties. Such statements involve known and unknown risks, uncertainties and other factors and undue reliance should not be placed thereon. These forward-looking statements are not historical facts, but rather are based on current expectations, estimates and projections about KBDC, its current and prospective portfolio investments, its industry, its beliefs and opinions, and its assumptions. Words such as 'anticipates,' 'expects,' 'intends,' 'plans,' 'will,' 'may,' 'continue,' 'believes,' 'seeks,' 'estimates,' 'would,' 'could,' 'should,' 'targets,' 'projects,' 'outlook,' 'potential,' 'predicts' and variations of these words and similar expressions are intended to identify forward-looking statements. These statements are not guarantees of future performance and are subject to risks, uncertainties and other factors, some of which are beyond KBDC's control and difficult to predict and could cause actual results to differ materially from those expressed or forecasted in the forward-looking statements including, without limitation, the risks, uncertainties and other factors identified in KBDC's filings with the SEC. All forward-looking statements speak only as of the date of this press release. KBDC does not undertake any obligation to update or revise any forward-looking statements or any other information contained herein, except as required by applicable law.

Scientists Discovered a Genetic Mutation That May Protect Against Alzheimer's
Scientists Discovered a Genetic Mutation That May Protect Against Alzheimer's

Yahoo

time13-07-2025

  • Health
  • Yahoo

Scientists Discovered a Genetic Mutation That May Protect Against Alzheimer's

A new study suggests a gene mutation could have a protective effect against Alzheimer's. The research looked specifically at blood stem cells, which live in the bone marrow and make different types of blood cells. Here's what you should know about the blood stem cell mutation and what this means for you. Genetic mutations aren't always a bad thing. A groundbreaking new study suggests that mutations on a single gene may actually be beneficial when it comes to Alzheimer's disease. The study, which was published in the journal Cell Stem Cell, looked at blood stem cells' interaction with the brain, and how mutations on a single gene can protect against Alzheimer's. 'We now know that these cells that circulate in the blood also have the capacity to go into the brain,' says Katherine King, MD, PhD, study co-author and professor at the Baylor College of Medicine. 'That's important in something like Alzheimer's disease.' Here's what the research found, plus what it suggests for the future of Alzheimer's treatment. Meet the experts: Clifford Segil, DO, is a neurologist at Providence Saint John's Health Center in Santa Monica, CA; Katherine King, MD, PhD, is a study co-author and professor at the Baylor College of Medicine For the study, Dr. King and her fellow researchers looked at blood stem cells in mice and humans. They discovered that people and mice with specific blood stem cell mutations in a gene called TET2 were less likely to develop Alzheimer's disease than those without the mutation. As a result, the researchers concluded that there appears to be a 'protective effect' of this mutation. Blood stem cells, a.k.a. hematopoietic stem cells, live in the bone marrow and make different types of blood cells, including red blood cells, immune cells, and platelets, Dr. King explains. 'Immune cells protect us from infections, but they have an important role in helping the body stay healthy. That includes 'taking out the trash,'' Dr. King explains, referring to cellular waste. 'Our tissues normally produce waste and sometimes get injured. We have to clear out the injured cells to make way for healthy cells.' As you age, these blood stem cells can develop mutations. The mutations don't usually cause issues, but sometimes they cause cells to divide more than others and create a clone. That's called clonal hematopoiesis, and it's been linked to a higher risk for conditions like cardiovascular disease, leukemia, stroke, and more. But blood stem cell mutations in the TET2 gene can travel to the brain, where they may actually help clear out damaged tissue that naturally accumulates with age, Dr. King explains. 'In Alzheimer's disease, there are proteins or parts of cells that are damaged tissues that build up,' she says. 'We have to get rid of them or clear them away.' This new research essentially found that the mutated blood stem cells can go to the brain and help with the process of 'clearing out the trash,' King says. The discovery has opened the door for potential new treatments, although we're not quite there yet. 'Supportive cells to brain neurons may be a future potential target for a therapy in humans, as removing old damaged cells may be a reasonable way to fight aging in the brain,' says Clifford Segil, DO, a neurologist at Providence Saint John's Health Center in Santa Monica, CA. A future treatment that's able to help healthy cells remove old or unhealthy cells may help improve brain health, he says. But Dr. King says this process is a little complicated. 'The change in stem cells isn't totally benign: There are risks and benefits,' she says. 'The same change that may be helpful with Alzheimer's disease is also linked with other dangerous things like heart disease and strokes.' Dr. King says it may be possible to engineer stem cells to follow specific pathways to help enhance the function of the brain without causing risks—but that's still TBD. You Might Also Like Can Apple Cider Vinegar Lead to Weight Loss? Bobbi Brown Shares Her Top Face-Transforming Makeup Tips for Women Over 50

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